September 23, A new study suggests that a chromosomal instability score may help guide treatment choices for patients with cancer. August 8, A study in mice may have identified a way to help overcome resistance to targeted cancer drugs known as PI3K inhibitors.
Treating Cancer without Harming the Heart Cancer treatments research paper March 9, Initial results from a series of three small clinical trials of a targeted cancer therapy called larotrectinib suggest that it may be effective in patients—children and adults—with a wide variety of cancer types.
The finding may explain why many patients treated with the drug develop hearing loss and could point toward potential ways to prevent it.
Preliminary results from an NCI-sponsored study of an immunotherapy drug show that people with HIV can safely participate in clinical trials. February 9, A small but growing number of patients with cancer are being treated with oncolytic viruses, which infect and kill tumor cells.
An article about research to improve CAR T-cell therapy and expand its use. November 8, Research studies show tests that analyze tumor DNA in blood, called liquid biopsies, may help detect cancer early, guide precision cancer treatment, and track treatment response.
July 21, The FDA has cleared a cooling cap—a device designed to reduce hair loss during chemotherapy called the DigniCap Scalp Cooling System—for use by patients with any type of solid tumor. July 20, A study in mice sheds light onto how some chemotherapies cause diarrhea.
Such a test could potentially identify toxic side effects earlier in the drug development process. A Conversation with Dr. September 12, In a large study, patients with nonmetastatic breast, lung, or colorectal cancer who chose alternative therapies had substantially worse survival than patients who Cancer treatments research paper conventional cancer treatments.
Findings from three arms were released at the ASCO annual meeting, adding to findings from one arm released in February 5, Using mouse models of cancer, researchers found that altering the gut microbiome could affect whether tumors responded to checkpoint inhibition.
July 6, Researchers who study exceptional responders—patients who have dramatic and long-lasting responses to treatments for cancer that were not effective for most similar patients—met recently to discuss the state of the science in this emerging field.
June 6, The CFH antibodies killed tumor cells in cell lines of several cancer types and slowed tumor growth in mouse models of brain and lung cancer, without evidence of side effects. February 13, Two compounds that target components of the circadian clock killed several types of cancer cells in the lab and slowed the growth of brain tumors in mice without harming healthy cells, a new study showed.
The combination was more effective and safer if the two inhibitors were given in a specific sequence. July 6, A new study has linked age with how well patients with melanoma responded to treatment with immune checkpoint inhibitors. Experiments in mice suggested that the response pattern may be due to an age-related shift in the kinds of immune cells in tumors.
James Gulley discusses cancer checkpoint inhibitors, their impact on patient care, and future directions for these therapies. June 20, FDA approved pembrolizumab for patients with solid tumors that have specific genetic features, called mismatch repair deficiency and high microsatellite instability.
December 7, Some cancer treatments may damage the heart, and researchers from the fields of oncology and cardiology are working to find ways to prevent, manage, and possibly even reverse these side effects.
June 29, The NCI Experimental Therapeutics NExT program works with researchers and top scientific experts to advance promising or novel cancer therapies from the earliest stages of research to human clinical trials.
March 21, Researchers have used adult stem cells to create a tool for ranking how toxic a group of cancer drugs, called tyrosine kinase inhibitors, are to human heart cells.
October 14, The recently launched COMET study will examine whether educating patients with cancer about genetic testing will increase their knowledge and reduce their stress levels after receiving genomic testing results.
July 21, A drug currently used to treat several psychiatric conditions can help prevent nausea and vomiting in patients receiving chemotherapy, a large clinical trial showed. October 3, When given at the same time, two immune checkpoint inhibitors were ineffective against breast cancer growth in mice, a new study found.
But research now suggests that these treatments also work against cancer by spurring an immune response. September 11, Dr. August 11, A drug used to treat several blood cancers, ibrutinib, has been approved by FDA to treat chronic graft-versus-host disease, making it the first approved therapy for this potentially fatal side effect of cancer-related stem cell transplants.
April 4, Two independent groups of researchers have fused a TGF-beta receptor to a monoclonal antibody that targets a checkpoint protein. The findings could be the basis for developing new treatments for patients with cancer who develop gastrointestinal side effects from chemotherapy.
The findings were published in Nature Medicine. NCI study identifies essential genes for cancer immunotherapy Posted: New approach to immunotherapy leads to complete response in breast cancer patient unresponsive to other treatments Posted: March 20, Using a new tool for editing genomes, known as CRISPR, researchers have genetically engineered immune cells and improved the ability of these cells to kill cancer cells in mice.What does it take to outsmart cancer?
Research. We've invested more than $ billion in cancer research sinceall to find more – and better – treatments, uncover factors that may cause cancer, and improve cancer patients' quality of life.
These are cancer treatments using medical technologies (interventional treatments) including laser treatment, photodynamic therapy and cryotherapy. Complementary and alternative therapies Learn what complementary and alternative therapies are, how they're used and what research there is.
Cancer Treatment Research. Cancer & Public Health. Cancer Health Disparities. Childhood Cancers. Clinical Trials.
Some cancer treatments may damage the heart, and researchers from the fields of oncology and cardiology are working to find ways to prevent, manage, and possibly even reverse these side effects. Breast cancer research The efforts to find a cure for breast cancer are ongoing.
Researchers develop and test new drugs and other treatments all the time. This research begins in the lab. Lab research helps find treatments which might benefit Research on Breast Cancer Treatment. There are many types of cancer treatment.
The types of treatment that you receive will depend on the type of cancer you have and how advanced it is. Some people with cancer will have only one treatment. But most people have a combination of treatments, such as surgery with chemotherapy and/or.
When looking at cancer as a metabolic disease, mitochondria (the engine of the cell) plays a key role in tumor development (Ref.).
As a result, mitochondria inhibitors are important tools to be included in an anticancer treatment strategy.Download